Men's Hormonal Health

How to Correctly Administer HCG Injections

HCG injections are a common adjunct to testosterone replacement therapy among males. When combined with testosterone and estrogen control (aromatase inhibitor) as described in the testosterone trifecta plan, it can help maintain long term fertility and hormonal balance.

HCG Primer

Human chorionic gonadotropin is primarily known for it's production during human pregnancy by the developing embryo after conception, and later followed by syncytiotrophoblasts in the placenta.

Vial of HCG for Injections

What the commercials don't tell you.. "the pregnancy hormone" found in urine on a pregnancy test, is actually HCG!

Additionally, HCG can also be produced by some cancerous tumors, which in some cases can help towards a positive diagnosis.

However for our purposes, we're interested in it's use as a pituitary analog of HCG, known as luteinizing hormone (LH). In males, LH is a signal from the pituitary to the testes to produce more testosterone.

An intricate feedback system that in some cases becomes dysfunctional in men with low testosterone, also referred to as hypogonadism.

Routes for Administration

Currently, the only viable way to administer HCG is through injection, most favourably as subcutaneous (under the skin).

Be vigilant of bogus "oral HCG formulations" being hocked in the supplemental market. Most are homeopathic remedies which contain virtually no human chorionic gonadotropin what so ever!

As a glycoprotein, the idea of absorption through oral supplementation is moot anyways. Your best bet in obtaining HCG is through prescription via a licenced medical practitioner, specializing in hormone replacement therapy.

HCG Levels and Testosterone Dosing Schedules

There are a number of protocols currently favoured in the medical community. One common dosage pattern is a 500 IU HCG injection on days 5 and 6, used concomitantly with a weekly 100 mg testosterone injection on day 7.

If you prefer a shorter dosage pattern, as I do, due to the half-life concerns of testosterone and to maintain more stable levels, shots of both can be made every 2nd or 3rd day... Shooting for a combined weekly total of 1000 IU of HCG and 100 mg of testosterone.

Administration Procedure

Due to HCG being carried in a water based solution, it's viscosity is much less compared to oil based testosterone preparations. This allows for easier use of smaller gauge needles (30G or 31G), which contributes to faster injection times, and overall a more pleasant experience.

Depending on your prescription, most HCG vials dispensed at pharmacies will contain 10,000 IU of HCG dissolved in 10 ml of bacteriostatic water. Therefore if 500 IU of HCG is the desired dosage, one would extract 0.5 ml of solution.

  • 10000 IU/10 ml = 1000 IU/ml
  • 500 IU = 0.5 ml

Appropriate Storage of HCG

If you receive your HCG through prescription, most pharmacies will premix the HCG powder with bacteriostatic water. After mixing, it can then degrades rather quickly, therefore storage in a refrigerator is extremely important.

With optimal refrigerator conditions 3 to 5 degrees C (37 to 41 degrees F), your HCG should last approximately 30 days, before it starts becoming non-therapeutic.

Some people have used pregnancy tests to help determine the quality of their HCG towards it's due date. However I can't vouch for the accuracy of that practice.

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